教师基本信息:

姓名：马建龙

职称：青年研究员

邮箱：[email protected]

个人简介：

马建龙，男，青年研究员，博士生导师。2018年获西南大学发育生物学专业博士学位，2019-2023年在西南大学从事博士后研究，2024年加入做爱电影 任青年研究员。近年来以第一作者或通讯作者（含共同）在PNAS、Hepatology（2篇）、NPJ Regenerative Medicine和Development等期刊上发表多篇研究论文。

研究方向：

本课题组以斑马鱼和小鼠为主要模式动物，以肝脏等消化器官再生修复的细胞和分子机制及相关药物的开发为主要研究方向。

招生专业：

发育生物学、生物化学与分子生物学、遗传学、细胞生物学、生理学、生物医学

代表性论文：

1)    Kai Gang, Qi Chen, Junhui Sun, Tingwei Zhang, Pengcheng Cai, Rui Ni, Jianlong Ma*. (2025). Khdrbs1 drives re-differentiation of bipotential progenitor cells by inhibiting p53 in zebrafish biliary-mediated liver regeneration. Development. 152(4): DEV204266.

2)    Jianlong Ma^#, Yang Chen^#, Jingmei Song, Qingfeng Ruan, Lianghui Li, Lingfei Luo*. (2025). Establishment and application of a zebrafish model of Werner syndrome identifies sapanisertib as a potential antiaging drug. PNAS. 122(5): e2413719122.

3)    Xintao Zhang, Huijuan Liu, Pengcheng Cai, Zhuofu Huang, Jianlong Ma*, Lingfei Luo*. (2025). Mdka produced by the activated hepatic stellate cells drives bipotential progenitor cell redifferentiation during zebrafish biliary-mediated liver regeneration. Hepatology. 81(5): 1400-1415.

4)    Jianlong Ma^#, Zhuolin Yang^#, Zhuofu Huang, Linke Li, Jingliang Huang, Jingying Chen, Rui Ni, Lingfei Luo, Jianbo He*. (2023). Rngtt governs biliary-derived liver regeneration initiation by transcriptional regulation of mTORC1 and Dnmt1 in zebrafish. Hepatology. 78(1): 167-178.

5)    Jianlong Ma^#, Yayun Gu^#, Juanjuan Liu^#, Jingmei Song^#, Tao Zhou, Min Jiang, Yang Wen, Xuejiang Guo, Zuomin Zhou, Jiahao Sha, Jianbo He, Zhibin Hu, Lingfei Luo*, Mingxi Liu*. (2022). Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish. Cellular and Molecular Life Sciences. 80(1): 19.

6)    Jingmei Song^#, Jianlong Ma^#, Xing Liu, Zhuofu Huang, Lianghui Li, Linke Li, Lingfei Luo, Rui Ni, Jianbo He*. (2023). The MRN complex maintains the biliary-derived hepatocytes in liver regeneration through ATR-Chk1 pathway. NPJ Regenerative Medicine. 8(1): 20.

7)    Junqin Yu^#, Jianlong Ma^#, Yanfeng Li, Yang Zhou, Lingfei Luo, Yun Yang*. (2023). Pax4-Ghrelin mediates the conversion of pancreatic ε-cells to β-cells after extreme β-cell loss in zebrafish. Development. 150(6): dev201306.

8)    Junhui Sun, Qi Chen, Jianlong Ma*. (2022). Notch-Sox9 Axis Mediates Hepatocyte Dedifferentiation in KrasG12V-Induced Zebrafish Hepatocellular Carcinoma. International Journal of Molecular Sciences. 23(9):4705.

^#共同第一作者，*通讯作者